Tear Em Asunder

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babybull

Joined: 08/28/2014 Posts: 11546
Likes: 1986


Repost


Abstract:

The emergence of coronavirus disease 2019 (COVID-19) is caused by the 2019 novel coronavirus (2019-nCoV). The 2019-nCoV first broke out in Wuhan and subsequently spread worldwide owing to its extreme transmission efficiency. The fact that the COVID-19 cases and mortalities are reported globally and the WHO has declared this outbreak as the pandemic, the international health authorities have focused on rapid diagnosis and isolation of patients as well as search for therapies able to counter the disease severity. Due to the lack of known specific, effective and proven therapies as well as the situation of public-health emergency, drug repurposing appears to be the best armour to find a therapeutic solution against 2019-nCoV infection. Repurposing anti-malarial drugs and chloroquine (CQ)/ hydroxychloroquine (HCQ) have shown efficacy to inhibit most coronaviruses, including SARS-CoV-1 coronavirus. These CQ analogues have shown potential efficacy to inhibit 2019-nCoV in vitro that leads to focus several future clinical trials. This review discusses the possible effective roles and mechanisms of CQ analogues for interfering with the 2019-nCoV replication cycle and infection.

(In response to this post by Ramfucious)

Posted: 01/21/2021 at 9:33PM



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Current Thread:
 
  
So...Hydroxychloroquine -- Dubya Why Oh 01/21/2021 6:18PM
  Meant to go under BB ** -- Ramfucious 01/21/2021 9:08PM
  HCQ works! ** -- babybull 01/21/2021 8:37PM
  As a great malaria treatment! ** -- nateDiggsCSU 01/21/2021 9:22PM
  Link ** -- babybull 01/21/2021 9:40PM
  Where?! ** -- nateDiggsCSU 01/21/2021 9:46PM
  Repost -- babybull 01/21/2021 9:33PM
  Where’s the link? ** -- Ramfucious 01/21/2021 10:17PM
  True. If you have malaria. Not so much for Covid. ** -- 60s Rammie 01/21/2021 9:06PM
  Latest facts as of Dec.. -- babybull 01/21/2021 9:32PM
  Wait.....what? ** -- Dubya Why Oh 01/21/2021 6:45PM
  You can't make this stuff up -- CSURamFan  01/21/2021 6:54PM
  She is a stanford law grad. 🙄 ** -- Rampage 01/21/2021 8:16PM

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